ND Sieving Matrix

Advantages:

• Unique buffer system that is designed specifically to increase the separation of non-denatured DNA fragments: 8bp resolution at 916 bp with 22 cm separation length in 19 min (see plot below) 
• Proprietary co-polymer with excellent long-term stability (shelf-life > 6 months at room temperature) and compatibility with our unique buffer system
• No capillary coating required: can be used with bare, or "uncoated", capillary
• Moderately-low viscosity (about 1000 - 2600 mPa-sec)^*: Allows relatively straight-forward capillary filling on most systems.

^*Viscosity varies for different applications such as short vs. long capillaries or size range.

Uses:

• Mutation analysis, including thermal-gradient and chemical-gradient electrophoresis: the higher resolution makes it possible to discover more mutations.
• Single-stranded conformational polymorphism.
• Fragment size analysis of PCR product and restriction digests, avoiding the need for a "denaturing" step and offering faster separation times compared to ssDNA analysis.

 Please contact us for information on how to obtain a test sample for your application.